These ganglion cysts arise from an area of weakness in the joint capsule and are filled with a clear fluid which "leaks" from the wrist joint. Initially, they can be treated by needle drainage, but recurrence rates after this treatment are often 50% or more. If the cysts do recur, they are then treated by surgical excision.

An incision is placed over the cyst, the cyst is isolated, and the stalk is tracked down into the wrist joint. The joint capsule is reapproximated, the skin closed, and the wrist immobilied. It may be 1-2 weeks before the hand returns to normal activities.

This procedure is usually performed under general anesthesia in the hospital, but patients are discharged the same day.